DrugScreening相关论文
类风湿关节炎(RA)是一种影响多关节的自身免疫性疾病,其特征是关节的进行性炎症和破坏、畸形、活动能力丧失、甚至永久性残疾.尽管......
The baker\'s yeast Saccharomyces (S.) cerevisiae is a single-celled eukaryotic modelorganism widely used in research o......
Detection of simultaneous glutamate and GABA release from primary cortical neuronal cultures by RT-H
Objective Synaptic transmission is conducted by neurotransmitters released from nerve terminals.Neurotrans-mitter releas......
Major depression is a common mood disorder which jeopardizes our health; hitherto almost all of available antidepressant......
Establishment and Application of a New Cell-based High-throughput Model for SIRT1 Upregulators in RI
Aim: To find novel SIRT1 upregulators by establishment a new in vitro drug screening model.Methods: The recombined plasm......
Condylomata acuminata (CA) induced by low-risk human papillomaviruses (HPVs) is one of the most common sexually transmit......
Rapid screening for 61 central nervous system drugs in plasma using weak cation exchange solid-phase
Rapid and accurate screening for toxicants/chemicals in a broad range is an important element in systematic toxicologica......
Limitations of monolayer culture conditions have motivated scientists to explore new models that can recapitulate the ar......
High-efficient zebrafish(embryo)handling platforms are crucially needed to facilitate the deciphering of the increas......
研究人膀胱肿瘤对化疗药物反应性，筛选对个体敏感的化疗药莪。方法采用四氮唑蓝法对手术切除的２７例膀胱肿瘤新鲜标本进行顺铂，保尔佳，丝......
Traditional two-dimensional(2D)cell cultures lack the extracellular matrix(ECM)-like structure or dynamic fluidic micro-......
Recently, efforts have been made to reevaluate old drugs with a view to determining their potential as an alternative an......
会议
毛细管电泳、变性色谱、免疫吸附、DNA测序方法等已广泛用于DNA碱基错配、氧化缺失、链断裂等变化的检测,但有时如进行药物筛选时,......
Apoptosis has been considered as the only form of regulated cell death for a long time. However, a novel form of program......
HIV/AIDS is one of the most serious public health challenges globally. Despite the great efforts that are being devoted ......
天然产物是药物发现与筛选的物质基础，高效、快速的药物筛选技术是获得天然产物线索化合物的重要前提。本文从药物研发环境、药物研......
本文作者在Ｅｉｍｅｒｉａ ｔｅｎｅｌｌａ细胞培养模型上研究了评价抗球虫剂的程序，包括投药时间、效果评定指标、药物有效浓度及毒性浓度、细胞培养有效浓度及......
